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Invitrogen™ CES1 Polyclonal Antibody
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Product Code. 16538801
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100 μL
Unit Size:
100µL
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16538801 100 μL 100µL
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Product Code. 16538801 Supplier Invitrogen™ Supplier No. PA595959

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RQKTEEELLE TTLKMKFLSL DLQGDPRESQ PLLGTVIDGM LLLKTPEELQ AERNFHTVPY MVGINKQEFG WLIPMLMSYP LSEGQLDQKT AMSLLWKSYP LVCIAKELIP EATEKYLGGT DDTVKKKDLF LDLIADVMFG VPSVIVARNH RDAGAPTYMY EFQYRPSFSS DMKPKTVIGD HGDELFSVFG APFLKEGASE EEIRLSKMVM KFWANFARNG NPNGEGLPHW PEYNQKEGYL QIGANTQAAQ KLKDKEVAFW TNLFAKKAVE KPPQTEHIEL; Positive Samples: Mouse liver, A-549, U-937; Cellular Location: Endoplasmic reticulum lumen.

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CES1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.51 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CES1
Gene Accession No. P23141, P23953, Q64176, Q8VCC2
Gene Alias ACAT; acyl coenzyme A:cholesterol acyltransferase; acyl-coenzyme A:cholesterol acyltransferase; Brain carboxylesterase hBr1; carboxyesterase ES-3; carboxylesterase 1; carboxylesterase 1 (monocyte/macrophage serine esterase 1); carboxylesterase 1A; carboxylesterase 1E; Carboxylesterase 1G; carboxylesterase 1-like; carboxylesterase 2 (liver); CE-1; CEH; Ces1; Ces-1; Ces1a; Ces1e; Ces1g; Ces1l; CES2; cholesteryl ester hydrolase; cocaine carboxylesterase; Eg; EG244595; Egasyn; Es22; Es-22; ES-HTEL; esterase 22; esterase-22; ES-x; Gm4976; hCE-1; HMSE; HMSE1; human monocyte/macrophage serine esterase 1; liver carboxylesterase 1; Liver carboxylesterase 22; liver carboxylesterase 3; methylumbelliferyl-acetate deacetylase 1; MGC117365; Monocyte/macrophage serine esterase; PCE-1; pI 5.5 esterase; REH; Retinyl ester hydrolase; serine esterase 1; SES1; Ses-1; TGH; triacylglycero; Triacylglycerol hydrolase
Gene Symbols CES1, Ces1a, Ces1c, Ces1e, Ces1g
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 287-566 of human CES1 (NP_0012574).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1066, 12623, 13884, 13897, 244595
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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