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Tocris Bioscience™ Cercosporamide

Product Code. 18064672
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Quantity:
331 μg
Unit Size:
331µg
This item is not returnable. View return policy

Product Code. 18064672

Brand: Tocris Bioscience™ 4500/331U

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This item is not returnable. View return policy

Description

Potent Mnk2 inhibitor

Cercosporamide is a potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2) and JAK3 (IC50 values are 11, 31 and 116 nM for Mnk2, JAK3 and Mnk1 respectively). Blocks eIF4E phosphorylation; exhibits antiproliferative and proapoptotic activity in cancer cells in vitro. Also inhibits Pkc1. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material (9aS)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9a-methyl-9-oxo-4-dibenzofurancaboxamide
CAS 131436-22-1
Quantity 331 μg
Target Mnk Inhibitors
Molecular Formula C16H13NO7
Purity 96%
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