Cephalothin sodium salt, Thermo Scientific™

Product Code	Brand	Quantity
15416999	Thermo Scientific Alfa Aesar J65607.03	1g
15426999	Thermo Scientific Alfa Aesar J65607.06	5g

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Cephalothin sodium salt is used to study the mechanism of liposome encapsulated antibiotics1, strategies for co-opting β-lactamases of Gram-negative bacteria for treatment of antibiotics2, and for immunology studies in relation to antibiotics.3 It is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP6 on bacterial cell wall mucopeptide synthesis.

Solubility
Soluble in water

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Chemical Identifiers

• CAS: 58-71-9
• Molecular Weight (g/mol): 418.414
• InChI Key: VUFGUVLLDPOSBC-XRZFDKQNSA-M
• PubChem CID: 23675321
• IUPAC Name: sodium;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

• Molecular Formula: C16H15N2NaO6S2
• MDL Number: MFCD00072025
• Synonym: 7-(2-Thienylacetamido)cephalosporanic acid sodium salt; Cephalotin sodium salt
• ChEBI: CHEBI:3542
• SMILES: CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)[O-].[Na+]

Specifications

• CAS: 58-71-9
• Color: White
• MDL Number: MFCD00072025
• Merck Index: 14,1982
• Solubility Information: Soluble in water
• SMILES: CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)[O-].[Na+]
• Molecular Weight (g/mol): 418.414
• ChEBI: CHEBI:3542
• Chemical Name or Material: Cephalothin sodium salt

• Odor: Odorless
• Molecular Formula: C16H15N2NaO6S2
• Beilstein: 4120706
• Synonym: 7-(2-Thienylacetamido)cephalosporanic acid sodium salt; Cephalotin sodium salt
• InChI Key: VUFGUVLLDPOSBC-XRZFDKQNSA-M
• IUPAC Name: sodium;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• PubChem CID: 23675321
• Formula Weight: 418.42

Safety and Handling

GHS H Statement
H334-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause an allergic skin reaction.

P261-P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P333+P313-P342+P311-P362-P501c

H315-H317-H319-H334-H335

missing translation for 'einecsNumber' : 200-394-6

missing translation for 'rtecsNumber' : XI0388300

missing translation for 'tsca' : No

Recommended Storage : Keep cold

Product Identifier

• Cephalothin sodium salt

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 2
• Respiratory sensitiser Category 1
• Skin corrosion/irritation Category 2
• Skin sensitiser Category 1
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H317-May cause an allergic skin reaction.
• H319-Causes serious eye irritation.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
• H335-May cause respiratory irritation.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.
• P332+P313-If skin irritation occurs: Get medical advice/attention.
• P333+P313-If skin irritation or rash occurs: Get medical advice/attention.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : Cefalotin sodium

RUO – Research Use Only