Invitrogen™ CEP290 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA560550

Product Code. 15748381

Description

Immunogen sequence: QVESINKELE ITKEKLHTIE QAWEQETKLG NESSMDKAKK SITNSDIVSI SKKITMLEMK ELNERQRAEH CQKMYEHLRT SLKQMEERNF ELETKFAELT Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.

This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.

Specifications

• Antigen: CEP290
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cep290
• Gene Alias: 3H11Ag; b2b1454Clo; b2b1752Clo; Bardet-Biedl syndrome 14 protein; Bardet-Biedl syndrome 14 protein homolog; BBS14; BC004690; Cancer/testis antigen 87; centrosomal protein 290; centrosomal protein 290kDa; centrosomal protein of 290 kDa; Cep290; CT87; CTCL tumor antigen se2-2; JBTS5; Kiaa0373; LCA10; Meckel syndrome, type 4; MKS4; monoclonal antibody 3H11 antigen; nephrocystin-6; nephrocytsin-6; Nphp6; POC3; POC3 centriolar protein homolog; prostate cancer antigen T21; rd16; RGD1311640; SLSN6; tumor antigen se2-2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80184
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O15078
• Gene Symbols: Cep290
• Immunogen: Recombinant protein corresponding to Human CEP290. Recombinant protein control fragment (Product #RP-97890).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG