Invitrogen™ CEP170 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583592

Product Code. 16370545

Description

Immunogen sequence: IPPLVHSKTP EGNNGRSGDP RPQAAEPPDH LTITRRRTWS RDEVMGDNLL LSSVFQFSKK IRQSIDKTAG KIRILFKDKD RNWDDIESKL RAESEVPIVK T Highest antigen sequence indentity to the following orthologs: Mouse - 94%, Rat - 34%.

The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined.

Specifications

• Antigen: CEP170
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CEP170
• Gene Alias: 4933426L22Rik; A330004A13Rik; AI195353; centrosomal protein 170; centrosomal protein 170kDa; centrosomal protein of 170 kDa; CEP170; FAM68A; KAB; KARP-1-binding protein; KARP1-binding protein; KIAA0470; XRCC5 binding protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9859
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry, Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5SW79
• Gene Symbols: CEP170
• Immunogen: Recombinant protein corresponding to Human CEP170. Recombinant protein control fragment (Product #RP-99492).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG