CEP-28122 mesylate salt, MedChemExpress

Product Code. 16499927

Brand: Medchem Express HY18030A

Description

MedChemExpress CEP-28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK inhibitor, with an IC50 value of 1.9 nM for recombinant ALK kinase activity. CEP-28122 has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 mesylate salt has good pharmacodynamic and pharmacokinetic activity.

CEP-28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK inhibitor, with an IC50 value of 1.9 nM for recombinant ALK kinase activity. CEP-28122 has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 mesylate salt has good pharmacodynamic and pharmacokinetic activity.

Specifications

• Chemical Name or Material: CEP-28122 mesylate salt
• Color: Off-White
• Purity Grade Notes: Research
• Molecular Formula: C₂₉H₃₉ClN₆O₆S
• Quantity: 5 mg
• Solubility Information: DMSO : ≥ 6.4 mg/mL (10.08 mM)
• SMILES: O=C([C@H]1[C@](C2)([H])C=C[C@]2([H])[C@H]1NC3=NC(NC4=CC=C5C(CC[C@@H](N6CCOCC6)CC5)=C4OC)=NC=C3Cl)N.O=S(C)(O)=O
• Molecular Weight (g/mol): 635.17
• Formula Weight: 635.17
• Percent Purity: 99.85%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-Kinase/protease

Research purposes only