Invitrogen™ CENPH Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5119017

Product Code. 17700434

Description

CENPH Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.

Specifications

• Antigen: CENPH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CENPH
• Gene Alias: 1700021I11Rik; 2410018A12Rik; 2610042E16Rik; 2810046K12Rik; AU044255; CENPH; CENP-H; centromere autoantigen H; centromere protein H; Enp; ICEN35; Interphase centromere complex protein 35; kinetochore protein CENP-H; LOC681185; similar to centromere autoantigen H
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 26886, 64946
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: Q9H3R5, Q9QYM8
• Gene Symbols: CENPH
• Immunogen: Recombinant protein Centromere Protein H. The antigen corresponds to amino acid range 1-247 of the target protein.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG