Invitrogen™ CENPF Monoclonal Antibody (7F11.2)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA531600

Product Code. 16335034

Description

Keep as concentrated solution. Positive Control: HeLa.

This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitosis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.

Specifications

• Antigen: CENPF
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.2
• Gene Accession No.: P49454
• Gene Symbols: CENPF
• Immunogen: Protein fragment expressed in E. coli corresponding to amino acids 1759-2093.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry, Immunocytochemistry
• Clone: 7F11.2
• Conjugate: Unconjugated
• Gene: CENPF
• Gene Alias: 6530404A22Rik; AH antigen; AI325968; cell-cycle-dependent 350K nuclear protein; CENF; CENPF; CENP-F; CENP-F kinetochore protein; centromere autoantigen F; centromere protein F; centromere protein F, (mitosin); centromere protein F, 350/400ka (mitosin); centromere protein F, 350/400kDa (mitosin); CILD31; hcp-1; im:7140452; im:7144238; im:7154719; im:7156761; kinetochore protein CENPF; Lek1; leucine, glutamic acid, lysine family 1 protein; mitosin; PRO1779; RP11-262H5.1; si:ch211-152h14.2; STROMS
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 1063
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid