Invitrogen™ CELSR3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA533425

Product Code. 15384681

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey (89%) Marmoset (84%).

CELSR3 is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.

Specifications

• Antigen: CELSR3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CELSR3
• Gene Alias: Adgrc3; adhesion G protein-coupled receptor C3; anchor protein; cadherin EGF LAG seven-pass G-type receptor 3; Cadherin family member 11; cadherin, EGF LAG seven-pass G-type receptor 3; cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila); CDHF11; Celsr3; EGFL1; EGF-like protein 1; EGF-like-domain, multiple 1; Epidermal growth factor-like protein 1; flamingo; flamingo homolog 1; FMI1; hFmi1; KIAA0812; Megf2; Megf3; mKIAA0812; multiple EGF-like domains protein 2; multiple epidermal growth factor-like domains 2; multiple epidermal growth factor-like domains protein 2; RESDA1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1951
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9NYQ7
• Gene Symbols: CELSR3
• Immunogen: Synthetic 19 amino acid peptide from N-terminal extracellular domain of human CELSR3.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG