Invitrogen™ CELSR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5115006

Product Code. 17217773

Description

Antibody detects endogenous levels of total CELSR2.

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.

Specifications

• Antigen: CELSR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CELSR2
• Gene Alias: ADGRC2; adhesion G protein-coupled receptor C2; cadherin EGF LAG seven-pas G-type receptor 2; cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; cadherin, EGF LAG seven-pass G-type receptor 2; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); CDHF10; Celsr2; EGFL2; EGF-like protein 2; EGF-like-domain, multiple 2; epidermal growth factor-like 2; epidermal growth factor-like protein 2; flamingo; Flamingo homolog; flamingo homolog 3; Flamingo1; flamingo-like protein celsr2; FLJ34118; FLJ42737; FLJ45143; FLJ45845; KIAA0279; MEGF3; mfmi1; mKIAA0279; Multiple EGF-like domains protein 3; multiple epidermal growth factor-like domains 3; multiple epidermal growth factor-like domains protein 3; seven-pass transmembrane cadherin
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1952, 53883, 83465
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9HCU4, Q9QYP2, Q9R0M0
• Gene Symbols: CELSR2
• Immunogen: A synthesized peptide derived from human CELSR2(Accession Q9HCU4), corresponding to amino acid residues K2627-P2677.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG