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Invitrogen™ CEACAM8 Recombinant Mouse Monoclonal Antibody (BW 250/183)

Product Code. 30087441
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Quantity:
200 μg
Unit Size:
200µg
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30087441 200 μg 200µg
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Product Code. 30087441 Supplier Invitrogen™ Supplier No. MA551806

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Description

Mouse Recombinant Monoclonal Antibody

This antibody binds the human CD66b, which is expressed on the surface of granulocytes.

This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CEACAM8
Applications Flow Cytometry, Functional Assay, Immunocytochemistry
Classification Recombinant Monoclonal
Clone BW 250/183
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene CEACAM8
Gene Accession No. P31997
Gene Alias carcinoembryonic antigen CGM6; carcinoembryonic antigen gene family member 6; carcinoembryonic antigen related cell adhesion molecule 8; carcinoembryonic antigen-related cell adhesion molecule 8; CD66b; CD67; CD67 antigen; CEACAM8; CGM6; NCA-95; non-specific cross-reacting antigen NCA-95
Gene Symbols CEACAM8
Host Species Mouse
Immunogen The original antibody was generated by immunizing mice with CEA positive adenocarcinoma cells preferably from lungs.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1088
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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