Invitrogen™ CDY2B Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5140322

Product Code. 17834840

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: RQTEKQKKLT WTTTSRIFSN NARRRTSRST KANYSKNSP Highest antigen sequence indentity to the following orthologs: Mouse - 38%, Rat - 41%.

CDY2B encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes.

Specifications

• Antigen: CDY2B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDY2B
• Gene Alias: CDY; CDY2; CDY2A; CDY2B; chromodomain protein, Y chromosome, 2 related; chromodomain protein, Y-linked, 2B; testis-specific chromodomain protein Y 2; testis-specific chromodomain protein Y protein 2 related; Y chromosome chromodomain protein 2B
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 203611
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y6F7
• Gene Symbols: CDY2B
• Immunogen: Recombinant protein corresponding to Human CDY2B. Recombinant protein control fragment (Product #RP-109109).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG