CDK9/Cyclin K Recombinant Human Protein

CDK9/Cyclin K Recombinant Human Protein

Brand:  Invitrogen PV4335

Product Code. 11593647

Description

CDK9 is a serine⁄threonine kinase that phosphorylates the c-terminal domain of the largest subunit of RNA polymerase II and is involved in cell cycle regulation, This protein is coexpressed and copurified with CyclinK.

Specifications

• Accession Number: NP_001252, NP_003849
• For Use With (Application): Cell Viability, Pharma and Biopharma, Cell Proliferation and Function, Protein Assays and Analysis, Target and Lead Identification and Validation, Kinase Assay
• Molecular Weight (g/mol): 46.9/44.9, 91.8kDa
• Quantity: 10μg
• Regulatory Status: For research use only. Not for use in diagnostic procedures
• Gene Alias: CDK9/cyclin K, TAK
• Assays: CDK9/cyclin K was pre-diluted in enzyme dilution buffer and assayed in 25mM MOPS (pH 7.2), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 100μM ATP, 200μg/mL CHKtide substrate peptide (KKKVSRSGLYRSPSMPENLNRPR) and trace [32P]-γ-ATP for 10 minutes at 30°C
• Product Type: CDK9/Cyclin K Recombinant Human Protein
• Species: Human
• Expression System: Baculovirus
• Protein Subtype: Serine/threonine kinase

• Concentration: 0.18mg/mL
• Gene ID (Entrez): 1025, 8812
• Name: CDK9/Cyclin K Recombinant Human Protein
• Storage Requirements: –80°C
• Packaging: 1 Each
• Common Name: CDK9/Cyclin K Recombinant Human Protein
• KinaseFamily: CDK and CHK
• Specific Reactivity: 2nmoles of phosphate transferred to CDK7/9tide peptide substrate (YSPTSPSYSPTSPSYSPTSPSKKKK) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 5μg/mL
• Protein Tag: His Tag
• Protein Family: Kinase and inhibitors
• Purity or Quality Grade: 70% by SDS-PAGE

For Research Use Only. Not for use in diagnostic procedures.