Invitrogen™ CDK5RAP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5116623

Product Code. 17249123

Description

Positive Samples: LO2, HeLa Immunogen sequence: GQRLLAEMDI QTQEAPSSTS QELGTKGPHP APLSKFVSSV STAKLTLEEA YRRLKLLWRV SLPEDGQCPL HCEQIGEMKA EVTKLHKKLF EQEKKLQNTM KLLQLSKRQE KVIFDQLVVT HKILRKARGN LELRPGGAHP GTCSPSRPGS.

CDK5RAP2 is a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein is localized to the centrosome and Golgi complex and interacts with CDK5R1 and pericentrin (PCNT). CDK5RAP2 plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: CDK5RAP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDK5RAP2
• Gene Alias: C48; CDK5 activator-binding protein C48; CDK5 regulatory subunit associated protein 2; CDK5 regulatory subunit-associated protein 2; CDK5RAP2; centrosomal protein 215 kDa; Centrosome-associated protein 215; centrosomin; Cep215; KIAA1633; MCPH3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55755
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.25 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q96SN8
• Gene Symbols: CDK5RAP2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1744-1893 of human CDK5RAP2 (NP_0607194).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG