Invitrogen™ CDK5RAP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583824

Product Code. 16380775

Description

Immunogen sequence: KLHNQEQVIK HLTESTNQKD VLLQKFNEKD LEVIQQNCYL MAAEDLELRS EGLITEKCSS QQPPGSKTIF SKEKKQSSDY EELIQVLKKE QDIYTHLVKS LQESDSINNL QAELNKIFAL RKQLEQDVLS YQNLRKTLEE QISEIRRR Highest antigen sequence indentity to the following orthologs: Rat - 66%, Mouse - 66%.

CDK5RAP2 is a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein is localized to the centrosome and Golgi complex and interacts with CDK5R1 and pericentrin (PCNT). CDK5RAP2 plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: CDK5RAP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDK5RAP2
• Gene Alias: C48; CDK5 activator-binding protein C48; CDK5 regulatory subunit associated protein 2; CDK5 regulatory subunit-associated protein 2; CDK5RAP2; centrosomal protein 215 kDa; Centrosome-associated protein 215; centrosomin; Cep215; KIAA1633; MCPH3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55755
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry, Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96SN8
• Gene Symbols: CDK5RAP2
• Immunogen: Recombinant protein corresponding to Human CDK5RAP2. Recombinant protein control fragment (Product #RP-106126).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG