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Invitrogen™ CDK3/cyclin E1 Recombinant Human Protein

CDK3/CyclinE1 is a member of the cyclin-dependent protein kinase family. Recombinant full-length human CDK3 and Cyclin E1 were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins.

£436.00 - £6530.00

Specifications

For Use With (Application) Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation
Formulation 50mM Tris-HCl pH 7.5, 150mM NaCl, 0.1mM EGTA, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol
Molecular Weight (g/mol) 61.3/73.4kDa
Storage Requirements Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
Gene Alias CDK3: None CyclinE1: CCNE1, CCNE
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Product Code Brand Quantity Price Quantity & Availability  
15478943
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Invitrogen™
PV6298
10μg
£436.00
10µg
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Estimated Shipment: 16-04-2024
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15488943
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Invitrogen™
PV6299
100μg
£1460.00
100µg
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Estimated Shipment: 23-04-2024
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15498943
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Invitrogen™
PV6300
1mg
£6530.00
1mg
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Estimated Shipment: 23-04-2024
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Description

Description

CDK3/CyclinE1 promotes entry into S phase, in part by activating members of the E2F family of transcription factors. CDK3 can also associate with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. The CDK3 gene has been mapped to chromosomal location of 17q22-qter, telomeric to the BRCA1 gene by somatic cell hybrids analysis. The presence of a single point mutation in the CDK3 gene from several Mus musculus strains commonly used in the laboratory has been reported.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Specifications

Specifications

Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation
61.3/73.4kDa
CDK3: None CyclinE1: CCNE1, CCNE
Recombinant
50mM Tris-HCl pH 7.5, 150mM NaCl, 0.1mM EGTA, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol
Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
Human
GST Tag
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