Invitrogen™ CDIP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA561940

Product Code. 15759741

Description

Immunogen sequence: CLINDFKDVT HTCPSCKAYI YTYKLLC Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death; loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.

Specifications

• Antigen: CDIP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDIP1
• Gene Alias: 2700048O17Rik; 5730403B10Rik; AU018521; AW742692; C16orf5; CDIP; CDIP1; cell death inducing protein; cell death inducing Trp53 target 1; cell death involved p53-target; cell death-inducing p53 target 1; cell death-inducing p53-target protein 1; Cell death-inducing protein; I1; Lipopolysaccharide-induced tumor necrosis factor-alpha-like protein; LITAFL; LITAF-like protein; Transmembrane protein I1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29965
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H305
• Gene Symbols: CDIP1
• Immunogen: Recombinant protein corresponding to Human CDIP1. Recombinant protein control fragment (Product #RP-101138).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG