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Invitrogen™ CDIP1 Polyclonal Antibody

Product Code. 12828842
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12828842 100 μg 100µg
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Product Code. 12828842 Supplier Invitrogen™ Supplier No. PA520697

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-20697 can be used with blocking peptide PEP-0812.

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death; loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDIP1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene CDIP1
Gene Accession No. Q9DB75, Q9H305
Gene Alias 2700048O17Rik; 5730403B10Rik; AU018521; AW742692; C16orf5; CDIP; CDIP1; cell death inducing protein; cell death inducing Trp53 target 1; cell death involved p53-target; cell death-inducing p53 target 1; cell death-inducing p53-target protein 1; Cell death-inducing protein; I1; Lipopolysaccharide-induced tumor necrosis factor-alpha-like protein; LITAFL; LITAF-like protein; Transmembrane protein I1
Gene Symbols CDIP1
Host Species Rabbit
Immunogen A 19 amino acid peptide near the center of human CDIP.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29965, 66626
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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