Invitrogen™ CDH8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA581597

Product Code. 16348604

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Rat Cadherin-8/CDH8.

CDH8 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.

Specifications

• Antigen: CDH8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDH8
• Gene Alias: AI851472; cad8; CADH8; Cadherin; cadherin 8; cadherin 8, type 2; Cadherin8; cadherin-8; Cdh8; Nbla04261
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 84408
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O54800
• Gene Symbols: CDH8
• Immunogen: Recombinant Rat Cadherin-8/CDH8 Protein (Met1-Met621).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG