Invitrogen™ CDH16 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA557589

Product Code. 15775481

Description

Immunogen sequence: NSHVVYQLLS PEPEDGVEGR AFQVDPTSGS VTLGVLPLRA GQNILLLVLA MDLAGAEGGF SSTCEVEVAV TDINDHAPEF ITSQIGPISL PEDVEPGTLV AMLTAIDADL EPAFRLMDFA IERGDTEGTF GLDWEPDS Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 76%.

The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-16, also known as Ksp-Cadherin, is a type I membrane protein which is kidney-specific. Cadherin-16 is expressed exclusively in the basolateral membrane of renal tubular epithelial cells. The human Ksp-cadherin gene (Cadherin-16) maps to chromosome 16q21-proximal 16q22. The mouse Ksp-cadherin gene was localized to a highly syntenic region of distal Chromosome 8.

Specifications

• Antigen: CDH16
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDH16
• Gene Alias: Cadherin; cadherin 16; cadherin 16, KSP-cadherin; cadherin-16; Cadherin-16 (CDH16); CDH 16; CDH16; Kidney-specific cadherin; KSP-cadherin; Ksp-cadherin antibody; UNQ695/PRO1340
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1014
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75309
• Gene Symbols: CDH16
• Immunogen: Recombinant protein corresponding to Human CDH16. Recombinant protein control fragment (Product #RP-90410).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG