Invitrogen™ CDH12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5112167

Artikelnummer. 17190024

Beskrivelse

CDH12 Polyclonal Antibody for Western Blot

CDH12 is a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.

Tekniske data

• Antigen: CDH12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDH12
• Gene Alias: Brain cadherin; brain-cadherin; Br-cadherin; Cadherin; cadherin 12; cadherin 12, type 2 (N-cadherin 2); cadherin, neural type, 2; cadherin-12; CDH12; CDHB; N-cadherin 2; neural type cadherin 2; neuronal cadherin 2; RGD1566350
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1010
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.03% ProClin 300; pH 7
• Gene Accession No.: P55289
• Gene Symbols: CDH12
• Immunogen: E. coli-derived Human CDH12 fragment.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG