Invitrogen™ Cdc7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA124588

Product Code. 11505463

Description

PA1-24588 detects CDC7-Related Protein Kinase (CDC7L1) in Human samples.

CDC7 is a cell division cycle 7 homolog protein that is critical for the G1/S transition and is also essential for initiation of DNA replication as cell division occurs. CDC7 is expressed in many normal tissues, but the overexpression of CDC7 may be associated with neoplastic transformation for some tumors and transformed cell lines. CDC7/DBF4 kinase promotes S phase by alleviating an inhibitory activity in Mcm4 that evolved to integrate several protein kinase. CDC7 encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.

Specifications

• Antigen: Cdc7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDC7
• Gene Alias: AI597260; Cdc7; CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1; Cdc7 Kinase; Cdc7l1; CDC7-like 1; CDC7-related kinase; cell division cycle 7; cell division cycle 7 (S. cerevisiae); cell division cycle 7 homolog; cell division cycle 7-like 1; cell division cycle 7-like protein 1; cell division cycle 7-related protein kinase; HsCDC7; Hsk1; huCDC7; MGC117361; MGC126237; MGC126238; MGC91067; muCdc7
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100060468, 100343407, 479955, 516094, 8317
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: O00311
• Gene Symbols: CDC7
• Immunogen: Synthetic 19 amino acid peptide from kinase domain of human CDC7.
• Quantity: 25 μg
• Primary or Secondary: Primary
• Target Species: Human, Canine, Rabbit, Bovine, Horse, Bat
• Product Type: Antibody
• Isotype: IgG