Invitrogen™ CDC45L Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA579021

Product Code. 15944595

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: rat testis tissue, rat thymus tissue, rat brain tissue, rat lung tissue, mouse testis tissue, mouse thymus tissue, mouse brain tissue, mouse lung tissue, mouse HEPA1-6 whole cell.

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenylation sites of this gene are reported.

Specifications

• Antigen: CDC45L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cdc45
• Gene Alias: CDC 45; CDC 45L; Cdc45; CDC45 cell division cycle 45 homolog; CDC45 like; CDC45L; CDC45L2; CDC45-related protein; Cell division control protein 45 homolog; cell division cycle 45; cell division cycle 45 homolog; cell division cycle 45-like 2; human CDC45; PORC PI 1; PORC-PI-1; UNQ374/PRO710
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12544, 287961, 8318
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: O75419, Q9Z1X9
• Gene Symbols: Cdc45
• Immunogen: E. coli-derived human CDC45L recombinant protein (Position: E166-A431).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG