Cdc25A Monoclonal Antibody (DCS-120), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA513794

Product Code. 11324923

Description

MA5-13794 targets CDC25A in IP, IHC (P) and WB applications and shows reactivity with Human and Rat samples. The MA5-13794 immunogen is purified recombinant CDC25A.

CDC25a is a member of the CDC25 family of phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C. These three genes function at different phases of the cell cycle. CDC25a is required for progression through G1 and S phases of the cell cycle. CDC25a activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.

Specifications

• Antigen: Cdc25A
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
• Gene Accession No.: P30304, P48964, P48965
• Gene Symbols: CDC25A
• Immunogen: Purified recombinant CDC25A
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: DCS-120
• Conjugate: Unconjugated
• Gene: CDC25A
• Gene Alias: CDC25 isoform A1-CAG; CDC25A; CDC25A2; CDC25A2-CAG isoform; Cdc25m3; cell division cycle 25A; D9Ertd393e; dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 12530, 171102, 993
• Content And Storage: 4° C
• Form: Liquid