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Invitrogen™ Cdc23 Polyclonal Antibody

Product Code. 12809102
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Quantity:
100 μg
Unit Size:
100µg
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12809102 100 μg 100µg
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Product Code. 12809102 Supplier Invitrogen™ Supplier No. PA520949

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Description

Rabbit Polyclonal Antibody

A suggested positive control is K562 cell lysate. PA5-20949 can be used with blocking peptide PEP-1063.

Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cdc23
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Cdc23
Gene Accession No. Q8BGZ4, Q9UJX2
Gene Alias 6030435O18; ANAPC8; anaphase promoting complex subunit 8; anaphase-promoting complex subunit 8; APC8; CDC23; CDC23 (cell division cycle 23, yeast, homolog); CDC23 cell division cycle 23; cell division cycle 23; cell division cycle 23 homolog; cell division cycle protein 23; cell division cycle protein 23 homolog; CUT23; cyclosome subunit 8; D18Ertd243e; zgc:56013
Gene Symbols Cdc23
Host Species Rabbit
Immunogen A 17 amino acid peptide near the center of human APC8.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 291689, 52563, 8697
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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