CD95 (APO-1/Fas) Mouse anti-Mouse, Biotin, Clone: 15A7, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-0951-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15249659

Quantity Price
1 £ 152.25 / 500µg
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Conjugate Biotin
Species Reactivity Mouse
Storage Requirements Store at 2-8°C. Do not freeze.
Antigen CD95 (APO-1/Fas)
Isotype IgG1
Format Conjugated
Clone 15A7
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Concentration 0.5mg/mL
Host Species Mouse
Applications Flow Cytometry
Quantity 500μg

The 15A7 monoclonal antibody reacts with mouse CD95 (Fas, Apo-1), a 40-50kDa member of the TNFR superfamily. CD95 is expressed by a broad range of hematopoietic and non-hematopoietic cells including monocytes, neutrophils, activated lymphocytes and fibroblasts. Interaction of CD95 on mature lymphocytes with its ligand (FasL) induces apoptosis and is thought to be important in peripheral tolerance. 15A7 reacts with mouse CD95 in BALB/c strain and a bit more weakly in C57Bl/6 strain. 15A7 does not induce apoptosis of Fas-expressing cells.