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CD95 (APO-1/Fas), Functional Grade, clone: EOS9.1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-0958-85

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15288527

  • £227.10 / 500Āµg


Estimated Shipment
06-07-2018
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Description

Description

Description: The EOS9.1 monoclonal antibody reacts with human CD95 (Fas, Apo-1), a 40-50kDa member of the TNFR superfamily. CD95 is expressed by a broad range of hematopoietic and non-hematopoietic cells including monocytes, neutrophils, activated lymphocytes and fibroblasts. Interaction of CD95 on mature lymphocytes with its ligand (FasL) induces apoptosis and is thought to be important in peripheral tolerance. EOS9.1 does not block binding of DX2, another antibody specific for human CD95.Applications Reported: The EOS9.1 antibody has been reported for use in flow cytometric analysis. EOS9.1 is also effective in inducing apoptosis in in vitro functional studies.Applications Tested: The EOS9.1 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay.Storage and handling: Use in a sterile environment.Filtration: 0.2μm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.
Specifications

Specifications

CD95 (APO-1/Fas)
Monoclonal
1mg/mL
PBS with no preservative; pH 7.2
P25445
ALPS1A, APO-1, APT1, Apo-1 Fas, CD95, FAS1, FASTM, TNFRSF6
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow CytometryĆ¾Functional Assay
EOS9.1
Functional Grade
FAS
Purified
FAS
IgM, kappa
500μg
Store at 2-8°C.
Primary
355
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