Invitrogen™ CD89 Recombinant Mouse Monoclonal Antibody (14A8 (14.1))

Mouse Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA551814

Product Code. 30088739

Description

This antibody binds CD89 in the extracellular domain 2, outside the IgA-binding site.

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: CD89
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: P24071
• Gene Symbols: Fcar
• Immunogen: The original antibody was generated by immunizing HCO12 trangene containing mice with recombinant soluble CD89 antigen.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Flow Cytometry, Functional Assay, Immunoprecipitation
• Clone: 14A8 (14.1)
• Conjugate: Unconjugated
• Gene: Fcar
• Gene Alias: CD89; CTB-61M7.2; Fc alpha receptor; Fc fragment of IgA receptor; Fc fragment of IgA, receptor for; FcalphaRI; FCAR; IgA Fc receptor; immunoglobulin A Fc receptor; immunoglobulin A Fc receptor transcript variant 1; immunoglobulin A Fc receptor transcript variant 3; immunoglobulin A Fc receptor transcript variant 7; immunoglobulin A Fc receptor transcript variant 9; immunoglobulin A Fc receptor transcript variant deltaEC1; immunoglobulin A Fc receptor transcript variant deltaEC1 delta TM/C; immunoglobulin alpha Fc receptor
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2204
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid