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CD87 (UPAR) Mouse anti-Human, PerCP-eFluor 710, Clone: VIM5, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-3879-42

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15579246

  • £231.74 / 100 tests


Estimated Shipment date
from Supplier 26-09-2017
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Disclaimers:

For Research Use Only.


Description

Description

This VIM5 monoclonal antibody reacts with human CD87, a GPI-linked receptor for urokinase plasminogen activator (uPA). By sequestering uPA, CD87 is involved in the conversion of plasminogen to plasmin on the leading edge of migrating cells, a process critical for chemotaxis. CD87 is expressed on the surface of monocytes, dendritic cells, and on activated T and NK cells. Interestingly, in granulocytes, CD87 expressed in the cytoplasm and on the cell surface. Non-hematopoietic cells such as endothelial cells, keratinocytes, and fibroblasts, also express this receptor. Finally, CD87 plays a role in cell adhesion and migration, angiogenesis, and tumor metastasis.

This monoclonal antibody has been reported to have neutralization activity.
Specifications

Specifications

CD87 (UPAR)
VIM5
PerCP-eFluor 710
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Urokinase plasminogen activator receptor, UPA Receptor
IgG1
RUO
Primary
Human