CD87 (UPAR) Mouse anti-Human, PerCP-eFluor 710, Clone: VIM5, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-3879-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15579246

Quantity Price
1 £ 231.74 / 100 tests
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Concentration 5μL (0.25μg)/test
Primary or Secondary Primary
Clone VIM5
Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Applications Flow Cytometry
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Isotype IgG1
Antigen CD87 (UPAR)
Quantity 100 tests
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Format Conjugated
Conjugate PerCP-eFluor 710
Gene Alias Urokinase plasminogen activator receptor, UPA Receptor

This VIM5 monoclonal antibody reacts with human CD87, a GPI-linked receptor for urokinase plasminogen activator (uPA). By sequestering uPA, CD87 is involved in the conversion of plasminogen to plasmin on the leading edge of migrating cells, a process critical for chemotaxis. CD87 is expressed on the surface of monocytes, dendritic cells, and on activated T and NK cells. Interestingly, in granulocytes, CD87 expressed in the cytoplasm and on the cell surface. Non-hematopoietic cells such as endothelial cells, keratinocytes, and fibroblasts, also express this receptor. Finally, CD87 plays a role in cell adhesion and migration, angiogenesis, and tumor metastasis.

This monoclonal antibody has been reported to have neutralization activity.