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CD86 (B7-2) Rat anti-Mouse, FITC, Clone: GL1, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-0862-81

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15288139

  • £48.89 / 50µg


EU Stock 4
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Disclaimers:

For Research Use Only.


Description

Description

The GL1 monoclonal antibody reacts with mouse CD86, an ∽80kDa surface receptor also known as B7-2. CD86 & CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed at low level on B cells, macrophages, and dendritic cells and is upregulated on B cells through a variety of surface stimuli including the BCR complex, CD40 and some cytokine receptors. CD86 is also expressed by activated mouse T cells and thioglycolate-elicited peritoneal cells. In addition to CD80 (B7-1), CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). This interaction plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation, supports its major contribution during the primary phase of an immune response.
Specifications

Specifications

CD86
GL1
FITC
Conjugated
Rat
50μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
B72, B7.2, B70, Ly-58
IgG2a
RUO
Primary
Murine