CD86, PE-Alexa Fluor 700, clone: BU63, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MHCD8624

Product Code. 10642584

Description

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.

Specifications

• Antigen: CD86, CD86 (B7-2)
• Classification: Monoclonal
• Conjugate: PE-Alexa Fluor 700
• Gene: CD86
• Gene Alias: B7-2, B7.2, B70, CD28LG2, LAB72, MGC34413, B-lymphocyte activation antigen B7-2, B-lymphocyte antigen B7-2, B7-2 antigen, BU63, CD28 antigen ligand 2
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: ASR, ASR/IVD
• Gene ID (Entrez): 942
• Content And Storage: Store at 2 - 8 °C.
• Form: Liquid

• Applications: Flow Cytometry
• Clone: BU63
• Formulation: PBS with BSA, sucrose and 0.1% sodium azide
• Gene Accession No.: P42081
• Gene Symbols: CD86
• Immunogen: B-lymphoblastoid cell line ARH 77
• Quantity: 0.5 mL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1