missing translation for 'onlineSavingsMsg'
Learn More

CD79a Mouse, PE, Clone: HM47, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0792-41

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15546826

  • £78.88 / 25 tests


Estimated Shipment date
from Supplier 26-09-2017
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

The monoclonal antibody HM47 recognizes the cytoplasmic domain of CD79a, also known as mb-1. CD79a is a 47kDa membrane glycoprotein that associates with CD79b to form the heterodimeric B cell receptor (BCR). This receptor is responsible for B cell signaling, resulting in activation, apoptosis or anergy. Expression of CD79a is found throughout development from the earliest pre-B cell to plasma cells. CD79 is expressed on B cell neoplasms and some non-B cell malignancies such as AML. Unlike other antibodies that can be masked in B cell neoplastic cells, HM47 is a reliable antibody for recognizing CD79a and, as such, is a good marker for B cells. Because several variants of CD79a exist, the exact location of the epitope may differ slightly. Nevertheless, in humans thie epitope is typically amino acids 208-222.

The HM47 antibody reacts to human, mouse, rat, dog, primates (rhesus, chimpanzee, macaque and baboon) pig, guinea rabbit, pig, horse, cow and chicken.
Specifications

Specifications

CD79a
HM47
PE
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
5μL (0.06μg)
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Ig-alpha, mb-1
IgG1
RUO
Primary
Rhesus