CD75/CD75s Mouse anti-Human, Alexa Fluor 647, Clone: ZB55, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 566350

Product Code. 15884969

Description

The ZB55 monoclonal antibody specifically recognizes the carbohydrate CD75 (lactosamines) and CD75s (sialylated lactosamines) antigens which are expressed in association with various glycolipids and glycoproteins. CD75 is expressed on mature B cells and germinal center B lymphocytes whereas CD75s is expressed on mature B cells. CD75 expression is lost on B cells differentiating to plasma cells whereas CD75s expression is lost on both germinal center B cells and B cells differentiating into plasma cells. CD75 and CD75s may be expressed by some T cells and can be useful markers for distinguishing different types of malignant B cells.

Alexa Fluor™ 647 conjugates are highly photostable and remain fluorescent over a broad pH range. The excitation and emission maxima are nearly identical to those of APC. However, APC tends to be brighter while Alexa Fluor™ 647 is more optimal for intracellular applications. This fluorochrome exhibits uncommon photostability, making it an ideal choice for use in fluorescence microscopy. Due to nearly identical excitation and emission properties but different spillover characteristics, APC and Alexa Fluor™ 647 cannot be used simultaneously.

Specifications

• Antigen: CD75/CD75s
• Clone: ZB55
• Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgM κ

• Classification: Monoclonal
• Conjugate: Alexa Fluor 647
• Gene Alias: CD75/CD75s, CDw75
• Immunogen: Human CD32 Peptides
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.