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  6. CD73 Monoclonal Antibody (eBioTY/11.8 (TY/11.8)), NovaFluor™ Red 725, eBioscience™, Invitrogen™

CD73 Monoclonal Antibody (eBioTY/11.8 (TY/11.8)), NovaFluor™ Red 725, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£136.00 - £264.00

Specifications

Antigen CD73
Clone eBioTY/11.8 (TY/11.8)
Concentration 0.1 μg/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 2
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17806701
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Invitrogen
M032T02R05 		25 μg This item is currently unavailable or has been discontinued.
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17836701
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Invitrogen
M032T03R05 		100 μg This item is currently unavailable or has been discontinued.
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Description

Description

CD73 (Ecto-5-prime-nucleotidase, 5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. CD73 consists of a dimer of 2 identical 70 kDa subunits bound externally to the plasma membrane by a glycosyl phosphatidyl inositol linkage. CD73 is used as a marker of lymphocyte differentiation. Consequently, a deficiency of CD73 occurs in a variety of immunodeficiency diseases. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from CD73 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. The CD73 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations. Defects in the CD73 gene can lead to the calcification of joints and arteries, and intestinal tuberculosis. Two transcript variants encoding different isoforms of CD73 have been found.
Specifications

Specifications

CD73
0.1 μg/Test
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; NTE; Purine 5-Prime-Nucleotidase
NT5E
Primary
4° C, store in dark, DO NOT FREEZE!
NT5E
eBioTY/11.8 (TY/11.8)
Flow Cytometry
NovaFluor Red 725
Rat
Mouse
Q61503
23959
IgG1
Affinity chromatography
Antibody
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