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  6. CD72 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

CD72 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Product Code. 16821704 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16821704 20 μL 20µL
16811704 150 μL 150µL
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Product Code. 16821704 Supplier Proteintech Supplier No. 134691AP20UL

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Description

Rabbit Polyclonal Antibody

CD72 is a transmembrane glycoprotein expressed as a homodimer especially in B cells, but also in other antigen presenting cells such as dendritic cells and macrophages. Through one of its immunoreceptor tyrosine-based inhibitory motives (ITIMs), CD72 interacts with tyrosine phosphatase SHP-1, thereby suppressing B cell responsiveness. Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72 and results in dissociation of SHP-1 from CD72, thus enables B cell activation.

Specifications

Antigen CD72
Applications Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CD72
Gene Accession No. P21854, P21855
Gene Alias CD72, CD72 molecule, CD72b, Lyb 2, LYB2
Gene Symbols Cd72
Host Species Rabbit
Immunogen CD72 Fusion Protein Ag4262
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12517, 971
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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