CD7 Mouse anti-Human, PE, Clone: 4H9, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-0078-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15536696

Quantity Price
1 £ 121.67 / 100 tests
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Primary or Secondary Primary
Conjugate PE
Clone 4H9
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 5μL (0.25μg)/test
Gene Alias Leu-9
Isotype IgG2a
Monoclonal or Polyclonal Monoclonal
Species Reactivity Human
Applications Flow Cytometry
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 100 tests
Regulatory Status RUO
Antigen CD7
Host Species Mouse

This 4H9 monoclonal antibody reacts with human CD7 (also known as Leu-9 or gp40), a 40kDa transmembrane glycoprotein belonging to the immunoglobulin superfamily. This molecule is expressed on peripheral blood T lymphocytes and natural killer cells, as well as on lymphoid and myeloid lineage precursors during adult hematopoiesis. Capable of providing a costimulatory signal and associating with CD3 and CD45, CD7 is involved in T cell activation.

CD7 has also been detected on numerous T cell-derived leukemias and lymphomias. In fact, because CD7 expression is greater on CD4+ T cells in classical Hodgkin’s lymphoma than in benign reactive lymph adenopathy, this molecule may be used as a diagnostic for Hodgkin’s lymphoma.

Blocking assays demonstrate that this clone recognizes the same epitope as clone 124-1D1.