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CD62L (L-Selectin) Monoclonal Antibody (DREG-56 (DREG56)), APC, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
£87.25 - £237.00
Specifications
Clone | DREG-56 (DREG56) |
---|---|
Concentration | 5 μL/Test |
Applications | Flow Cytometry |
Classification | Monoclonal |
Conjugate | APC |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15577956
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Affymetrix eBioscience
17-0629-42 |
100 Tests |
£237.00
100 tests |
Estimated Shipment: 23-05-2024 Log in to see stock. |
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15567956
|
Affymetrix eBioscience
17-0629-41 |
25 Tests |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: The DREG-56 monoclonal antibody reacts with human CD62L, a 76 kDa member of the selectin family. CD62L is expressed by neutrophils, monocytes, and subsets of T, B, and NK cells and binds a number of glycosylated, fucosylated, sulfated sialylated glycoproteins including CD34, glycam-1 and MAdCAM-1. These interactions mediate rolling of lymphocytes on activated endothelium at the sites of inflammation and homing of cells to the high endothelial venules (HEV) of peripheral lymphoid tissues. Applications Reported: The DREG-56 (DREG56) antibody has been reported for use in flow cytometric analysis. Applications Tested: The DREG-56 (DREG56) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.5µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.
The human CD62L is a 74-95 kDa glycoprotein member of the selectin family of adhesion receptors. L-Selectin is comprised of an aminoterminal C-type lectin binding domain, an epidermal growth factor-like domain, two short consensus repeat (SCR) sequences homologous to those found in complement binding proteins, a short spacer region, a transmembrane region and a short cytoplasmic region. Human CD62L (L-Selectin) is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes and polymorphonuclear cells.Specifications
DREG-56 (DREG56) | |
Flow Cytometry | |
APC | |
Mouse | |
Human | |
6402 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |
5 μL/Test | |
Monoclonal | |
Liquid | |
RUO | |
P14151 | |
SELL | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
SELL |
For Research Use Only.