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CD61 (Integrin beta 3) Monoclonal Antibody (2C9.G3), NovaFluor™ Yellow 570, eBioscience™, Invitrogen™

Armenian Hamster Monoclonal Antibody

Brand:  Invitrogen M053T02Y01

Additional Details : Weight : 0.02000kg

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Product Code. 17836236

  • £161.00 / 25µg
Estimated Shipment: 08-08-2024
to see stock.

Description

Description

CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets and their precursors. CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronectin, von Willebrand factor and vitronectrin. CD61 is a 105 kDa glycoprotein that associates with either the alpha 11b integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, Von Willebrand Factor, vitronectin and thrombospondin. The CD61 protein product is composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. CD61 is found along with the alpha IIb chain in platelets. Like other integrins, CD61 is known to participate in cell adhesion as well as cell-surface mediated signaling. Diseases associated with CD61 dysfunction include Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.
Specifications

Specifications

CD61 (Integrin beta 3)
Monoclonal
0.1 mg/mL
PBS with 0.09% sodium azide; pH 7.2
O54890
ITGB3
Affinity chromatography
RUO
16416, 29302
4° C, store in dark, DO NOT FREEZE!
IgG
Flow Cytometry
2C9.G3
NovaFluor Yellow 570
ITGB3
antigen CD61; BDPLT16; BDPLT2; beta3 integrin; CD61; EGK_08849; glycoprotein GPIIIa; glycoprotein IIIa; GP3A; GPIIIa; GT; INGRB3; integrin beta 3; integrin beta 3 (Cd61); integrin beta-3; integrin beta-3 subunit; integrin subunit beta 3; integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGB3; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet gpIIIa; platelet membrane glycoprotein IIIa
Armenian Hamster
25 μg
Primary
Mouse, Rat
Liquid
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