missing translation for 'onlineSavingsMsg'
Learn More

CD59 (Protectin), FITC, clone: OV9A2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-0596-42

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15556426

  • £124.73 / 100 tests


Estimated Shipment date
from Supplier 29-05-2018
Add to basket

Description

Description

Description: This OV9A2 monoclonal antibody reacts with human CD59, which is also known as Protectin. This GPI-linked membrane glycoprotein shares structural homology with the murine Ly-6 superfamily. CD59 is expressed on all human lymphocytes, monocytes, granulocytes, and erythrocytes. This protein is also expressed on non-hematopoietic cells, including endothelial cells and neurons. By binding the complement components C8 and C9, CD59 inhibits assembly of the membrane attack complex and cytolytic activity by complement. CD59 interacts with CD2 to modulate T cell adhesion, and also plays a role in T cell activation. Finally, altered expression of CD55 and CD59 on human peripheral blood cells has been observed in patients with systemic lupus erythematosus (SLE).Crossblocking studies indicate that the OV9A2 monoclonal antibody binds the same epitope as MEM-43.Applications Reported: This OV9A2 antibody has been reported for use in flow cytometric analysis.Applications Tested: This OV9A2 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD59 (Protectin)
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P13987
CD59, CD59 molecule complement regulatory protein, 1F5, EJ16, EJ30, EL32, G344, MIN1, MIN2, MIN3, MIRL, HRF20, MACIF, MEM43, MIC11, MSK21, 16.3A5, HRF-20, MAC-IP, p18-20
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
OV9A2
FITC
CD59
Conjugated
CD59
IgG1, kappa
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
966
Videos

For Research Use Only.