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CD54 (ICAM-1) Monoclonal Antibody (HA58), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
£91.00 - £265.00
Specifications
| Antigen | CD54 (ICAM-1) |
|---|---|
| Clone | HA58 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugate | PerCP-eFluor 710 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15324851
|
Affymetrix eBioscience
46-0549-42 |
100 Tests |
£265.00
Pack of 100 |
Estimated Shipment: 20-05-2024 Log in to see stock. |
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|
15539136
|
Affymetrix eBioscience
46-0549-41 |
25 Tests |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
ICAM-1 (intercellular adhesion molecule) has 7 potential N-linked glycosylation sites. It is a single chain glycoprotein of Ig supergene family, present on unstimulated endo-thelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1).
ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.Specifications
| CD54 (ICAM-1) | |
| Flow Cytometry | |
| PerCP-eFluor 710 | |
| Mouse | |
| Human | |
| 3383 | |
| IgG1 κ | |
| Affinity chromatography | |
| ICAM1 |
| HA58 | |
| Monoclonal | |
| Liquid | |
| RUO | |
| P05362 | |
| ICAM1 | |
| Primary | |
| Antibody |
For Research Use Only.