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CD51 (Integrin αV) Mouse, anti-Human, FITC, Clone: NKI-M9, STEMCELL Technologies
Mouse Monoclonal Antibody
£160.65 - £395.55
Specifications
| Antigen | CD51 (Integrin αV) |
|---|---|
| Clone | NKI-M9 |
| Applications | Immunoprecipitation, ELISA, Flow Cytometry, Functional Assay |
| Classification | Monoclonal |
| Conjugate | FITC |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17188741
|
Stemcell Technologies
60043FI.1 |
25 Tests |
£160.65
25 tests |
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|
17178741
|
Stemcell Technologies
60043FI |
100 Tests |
£395.55
100 tests |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
- The NKI-M9 antibody reacts with CD51 (vitronectin receptor α chain, or integrin αV), a type I transmembrane glycoprotein containing two subunits (125 kDa and 24 kDa) which are generated by post-translational cleavage and are linked by a disulfide bond
- CD51 associates non-covalently with integrin β1 (CD29), β3 (CD61), β5, β6, or β8 to form heterodimeric cell adhesion receptors for extracellular matrix components such as fibrinogen, collagen, fibronectin, laminin, osteopontin, thrombospondin, vitronectin, and von Willebrand factor
- For example, association of CD51 and CD61 forms the integrin αv/β3 receptor primarily involved in binding vitronectin
- CD51 is expressed broadly on many types of cells, including endothelial cells, fibroblasts, monocytes, macrophages, platelets (at relatively low levels), and osteoclasts
- It is also found on hepatoma, melanoma, and neuroblastoma cells
Specifications
| CD51 (Integrin αV) | |
| Immunoprecipitation, ELISA, Flow Cytometry, Functional Assay | |
| FITC | |
| Human | |
| Primary |
| NKI-M9 | |
| Monoclonal | |
| Mouse | |
| IgG2a κ |
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