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CD48 (SLAMF2) Hamster, anti-Mouse, APC, Clone: HM48-1, STEMCELL Technologies
Hamster Monoclonal Antibody
£160.65 - £500.85
Specifications
| Antigen | CD48 (SLAMF2) |
|---|---|
| Clone | HM48-1 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugate | APC |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17159221
|
Stemcell Technologies
60162AZ.1 |
25 μg |
£160.65
25µg |
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|
17149221
|
Stemcell Technologies
60162AZ |
100 μg |
£500.85
100µg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
- The HM48-1 antibody reacts with mouse CD48, a 45 kDa GPI-anchored glycoprotein and a member of the signaling lymphocyte activation molecule (SLAM) family and Ig superfamily
- SLAM family members play a role in multiple aspects of immune function including costimulation, cytotoxicity, and cytokine production
- CD48 also plays a role in cell adhesion and T cell activation
- In mice, CD48 is thought to be present on nearly all hematopoietic cells except neutrophils and ESLAM cells (CD45+EPCR+CD48-CD150+ hematopoietic stem cells with long-term self-renewal capacity)
- Ligands for CD48 include CD2 and CD244, binding of which helps to promote interactions between immune cells
- HM48-1 is reported to be capable of blocking CD48:CD2 and CD48:CD244 interactions in vitro and in vivo
- HM48-1 is also reported to inhibit the proliferative response of spleen cells to mitogens, inhibit CTL activity, and enhance the survival of cardiac allografts
Specifications
| CD48 (SLAMF2) | |
| Flow Cytometry | |
| APC | |
| Mouse | |
| Primary |
| HM48-1 | |
| Monoclonal | |
| Hamster | |
| IgG1 λ3 |
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