CD45R (B220) Rat anti-Canine, PE, Clone: YKIX753.22, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-5451-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15567006

Quantity Price
1 £ 152.25 / 100 tests
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Species Reactivity Canine
Conjugate PE
Applications Flow Cytometry
Isotype IgG2b
Monoclonal or Polyclonal Monoclonal
Antigen CD45R (B220)
Host Species Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 5μL (0.0075μg)/test
Primary or Secondary Primary
Quantity 100 tests
Clone YKIX753.22
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Format Conjugated

The YKIX753.22 monoclonal antibody reacts with canine CD45R. In dogs, CD45R is expressed on B cells and peripheral T cells. In addition, CD45 exists as multiple isoforms due to alternative splicing. Some isoforms of CD45 are CD45RA, CD45RB, or CD45RO depending on the exon used during transcription. The C-terminal domain of CD45 exhibits tyrosine phosphatase activity that enables signaling from by T cell and B cell receptors following activation.

This antibody has been reported to promote cell depletion via antibody-dependent cell-mediated cytotoxicity when used in conjunction with YKIX716.13.