CD45R (B220), PE, clone: YKIX753.22, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 12-5451-42
Code : NEW
Additional Details : Weight : 0.23750kg
DescriptionDescription: The YKIX753.22 monoclonal antibody reacts with canine CD45R. In dogs, CD45R is expressed on B cells and peripheral T cells. In addition, CD45 exists as multiple isoforms due to alternative splicing. Some isoforms of CD45 are CD45RA, CD45RB, or CD45RO depending on the exon used during transcription. The C-terminal domain of CD45 exhibits tyrosine phosphatase activity that enables signaling from by T cell and B cell receptors following activation.This antibody has been reported to promote cell depletion via antibody-dependent cell-mediated cytotoxicity when used in conjunction with YKIX716.13.Applications Reported: This YKIX753.22 antibody has been reported for use in flow cytometric analysis.Applications Tested: This YKIX753.22 antibody has been pre-titrated and tested by flow cytometric analysis of normal canine peripheral blood cells. This can be used at 5 μL (0.0075 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|