CD45.2 Mouse, anti-Mouse, Biotin, Clone: 104, STEMCELL Technologies

Mouse Monoclonal Antibody

Brand:  Stemcell Technologies 60118BT.1

Product Code. 17169141

Description

• The 104 monoclonal antibody reacts with mouse alloantigen CD45.2 (Ly5.2) expressed by all hematopoietic cells except mature erythrocytes and platelets in mouse strains A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, and 129
• Clone 104 does not react with leukocytes that express CD45.1 alloantigen
• CD45.2 is an allelic form of CD45 (Leukocyte common antigen), a 180 - 240 kD type I transmembrane glycoprotein
• CD45 is a member of the protein tyrosine phosphatase (PTP) family and functions in a number of immunoregulatory processes, including cell activation, growth, lymphocyte development, differentiation, and oncogenic transformation
• The isoforms of CD45 correlate to specific cell types, as well specific activation and maturation states of immune cells
• The 104 monoclonal antibody has been used extensively in adoptive cell transfer and bone marrow transplantation studies in mice, allowing for the differentiation of CD45.2- and CD45.1- expressing cells

Specifications

• Antigen: CD45.2
• Classification: Monoclonal
• Conjugate: Biotin
• Quantity: 50 μg
• Target Species: Mouse
• Cell Type: Granulocytes and Subsets, Hematopoietic Stem and Progenitor Cells, Lymphocytes, Myeloid Cells

• Applications: Flow Cytometry
• Clone: 104
• Host Species: Mouse
• Primary or Secondary: Primary
• Isotype: IgG2a κ