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  6. Invitrogen™ CD44H Monoclonal Antibody (OX49), PE, eBioscience™, Invitrogen™

Invitrogen™ CD44H Monoclonal Antibody (OX49), PE, eBioscience™, Invitrogen™

Product Code. 15238539
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100 μg
25 μg
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100µg
25µg
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15238539 25 μg 25µg
15248539 100 μg 100µg
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Product Code. 15238539 Supplier Invitrogen™ Supplier No. 12044480

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Description

Mouse Monoclonal Antibody

Description: This OX49 monoclonal antibody recognizes rat CD44H, which is also known as homing-associated cell adhesion molecule (H-CAM) or phagocytic glycoprotein-1 (Pgp-1). This isoform of CD44 is the cell surface receptor for hyaluronate, a component of the extracellular matrix. CD44H is highly expressed on hematopoietic and non-hematopoietic cells, and exists as multiple splice variants. CD44H plays a critical role in lymphocyte activation and homing. Applications Reported: This OX49 antibody has been reported for use in flow cytometric analysis. Applications Tested: This OX49 antibody has been tested by flow cytometric analysis of rat splenocytes. This can be used at less than or equal to 0.06 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

CD44 cell surface antigen is a 100kDa glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD44H
Applications Flow Cytometry
Classification Monoclonal
Clone OX49
Concentration 0.2 mg/mL
Conjugate PE
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Cd44
Gene Accession No. P26051
Gene Alias CD44; CD44 antigen; CD44 molecule (Indian blood group); CD44A; Cell surface glycoprotein CD44 (hyaluronate binding protein); ECMR-III; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; Hermes antigen; HUTCH-I; Hyaluronate receptor; METAA; PGP-1; PGP-I; Phagocytic glycoprotein 1; phagocytic glycoprotein I; RHAMM
Gene Symbols Cd44
Host Species Mouse
Purification Method Affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25406
Target Species Rat
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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