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CD44 Std./H-CAM Ab-4 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results in immunohistochemistry, western blotting, immunoprecipitation and flow cytometry experiments.
Brand: Epredia MS-668-P
This item is not returnable.
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Description
CD44 is a cell surface glycoprotein expressed on lymphocytes, monocytes, and granulocytes. CD44 is also known as homing cell adhesion molecule (H-CAM), Phagocytic glycoprotein-1 (PgP-1), ECM-III, HUTCH-1, or Hermes-1. CD44 has been implicated in cell migration, in lymphocyte homing, and in tumor metastasis. Ab-4 reacts with red cells pretreated with 2-aminoethylisothiouronium bromide (AET). Digestion of intact erythrocytes by trypsin treatment leaves a 50-54 kDa protein fragment attached to the membrane, while chymotrypsin leaves a somewhat similarly sized 51-56 kDa component that are recognized by Ab-4. This antibody enhances IL-2 production by CD2-transfected murine hybridoma stimulated by JY cells while it has no significant effect on IL-2 production by Jurkat cells stimulated with CD3, PMA, or CD2. Ab-4 enhances proliferation of PBL stimulated with CD2.Host Species: Mouse
Clone: 156-3C11
Isotype: IgG2a
Species Reactivity: Human, Baboon and Green Monkey. Does not react with rat. Others not tested.
Epitope: Resistant to digestion by trypsin and chymotrypsin
Immunogen: Stimulated human leukocytes
Molecular Weight: 80-95 kDa
Positive Control: HUVEC or HeLa cells, tonsil or esophageal CA
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native verified)
- Flow Cytometry
Specifications
| CD44 Std./H-CAM Ab-4 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 1 mL | |
| Oncogenesis | |
| Human, Non-human Primate | |
| IgG2a |
| Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
| 156-3C11 | |
| Unconjugated | |
| Stimulated human leukocytes | |
| IVD | |
| Primary | |
| Concentrated |
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