CD44 Rat, anti-Mouse, Alexa Fluor 488, Clone: IM7, STEMCELL Technologies

Rat Monoclonal Antibody

Brand:  Stemcell Technologies 60068AD.1

Product Code. 17198811

Description

• The IM7 antibody reacts with CD44 (Ly-24), an ∼80 - 95 kDa type 1 transmembrane glycoprotein involved in cell-cell and cell-matrix interactions
• CD44 is expressed on the surface of many cells, including leukocytes and hepatocytes, as well as endothelial, epithelial, and mesenchymal cells
• Expression levels increase upon activation of T and B cells, and memory cells exhibit a CD44 high phenotype
• CD44 binds many ligands, including hyaluronic acid, collagen, fibronectin, growth factors, and metalloproteinases, thus modulating processes such as lymphocyte activation, recirculation and homing, leukocyte rolling and aggregation, hematopoiesis, and tumor metastasis
• This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse CD4+ T Cell Isolation Kit (Catalog #19852), EasySep™ Mouse CD4+CD62L+ T Cell Isolation Kit (Catalog #18765), and EasySep™ Human Naive CD4+ T Cell Isolation Kit (Catalog #19555)

Specifications

• Antigen: CD44
• Classification: Monoclonal
• Conjugate: Alexa Fluor 488
• Quantity: 25 μg
• Target Species: Baboon, Cynomolgus, Rhesus Monkey, Chimpanzee, Human
• Cell Type: Mammary Cells, T Cells

• Applications: Immunohistochemistry, ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Clone: IM7
• Host Species: Rat
• Primary or Secondary: Primary
• Isotype: IgG2b κ