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CD42a Mouse anti-Human, eFluor 450, Clone: GR-P, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-0428-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15559676

  • £66.36 / 25 tests


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For Research Use Only.


Description

Description

This GR-P monoclonal antibody reacts with human CD42a, which is also known as glycoprotein IX (GPIX). CD42a is a 22kDa transmembrane protein that is constitutively expressed on platelets and megakaryocytes. CD42a associates with CD42b, CD42c, and CD42d to form the GPIb-V-IX complex, which binds the von Willebrand factor, an endothelial adhesion protein, to mediate platelet adhesion and activation. This binding results in platelet aggregation at sites of vascular injury. This receptor complex has also been demonstrated to bind thrombin, factors XI and XII, P-selectin, and Mac-1. Finally, a point mutation within the leucine-rich motif of CD42a has been linked to Bernard-Soulier syndrome.
Specifications

Specifications

CD42a
GR-P
eFluor™ 450
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Glycoprotein IX, GP9
IgG1
RUO
Primary
Human
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