CD40 Armenian Hamster anti-Mouse, Rat, Clone: HM40-3, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0402-85


UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg

Disclaimers: For Research Use Only.

Product Code. 15276937

Quantity Price
1 £169.00 / 500µg
Estimated Shipment date
from Supplier 31-10-2016
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Description and Specification


Antigen CD40
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry
Clone HM40-3
Concentration 0.5mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias TNFRSF5
Host Species Armenian Hamster
Isotype IgM
Quantity 500μg
Regulatory Status RUO
Species Reactivity Mouse, Rat
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.