CD4 Rat, anti-Mouse, APC, Clone: RM4-5, STEMCELL Technologies

Rat Monoclonal Antibody

Brand:  Stemcell Technologies 60017AZ

Product Code. 17108481

Description

• The RM4-5 antibody reacts with mouse CD4, an ∼55 kDa single-chain type 1 transmembrane glycoprotein and member of the immunoglobulin (Ig) superfamily; CD4 contains four extracellular Ig-like domains
• CD4 is expressed at relatively high levels by most thymocytes and a subpopulation of T cells (T helper/inducer cells), and at lower levels on dendritic cells
• CD4 binds to a non-polymorphic region of MHC II and acts as a co-receptor to the T cell receptor (TCR) in MHC II-restricted antigen recognition by enhancing the avidity of the association between the TCR and MHC II-antigen complex
• Binding of the RM4-5 antibody to CD4 inhibits ligand binding in vitro; binding of the RM4-5 antibody can be blocked by the clone GK1.5 antibody
• This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse CD4+ T Cell Isolation Kit (Catalog #19852) and EasySep™ Mouse CD25 Regulatory T Cell Positive Selection Kit (Catalog #18782)

Specifications

• Antigen: CD4
• Classification: Monoclonal
• Conjugate: APC
• Quantity: 100 μg
• Target Species: Mouse
• Cell Type: T Cells, T Cells, CD4+, T Cells, Regulatory

• Applications: Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Clone: RM4-5
• Host Species: Rat
• Primary or Secondary: Primary
• Isotype: IgG2a κ